https://www.newsweek.com/matrix-creator-red-pill-trans-allegory-mens-rights-activists-1523669
The red pill meaning is a deep rabbit hole on the internet.
Paste from the above article:
Obviously, the hormone therapy subtext in The Matrix does some undermining of The Red Pill's beliefs. Even Wachowski has denounced prominent people using the meme. When Tesla founder Elon Musk tweeted the phrase, "take the red pill," and Ivanka Trump quote-tweeted it with "Taken," Wachowski responded, "F**k both of you." While Trump and Musk did not express which brand of red pill they subscribed to, Wachowski's denouncement is telling.