if you have only played Betrayal at House once, give it another shot. I've had good times with the game.
Ticket to ride is on my want list, as well as Euphoria: Build a better dystopia
Oooo, almost forgot-
Star Wars Imperial Assault is another scenario driven game where its usually one vs the rest. 2-5p. I've only gone through the tutorial and the first two missions as GM, but the game is really well balanced.